Prophylactic and immune modulatory influences of Nigella sativa Linn. in broilers exposed to biological challenge
نویسندگان
چکیده
Background and Aim Prophylaxis and disease prevention is an essential strategy among biorisk management in poultry farms that stimulate and maintain the birds' immunity. The aim of this study was to investigate the prophylactic, and immune-stimulant influence of Nigella sativa Linn. in broilers under biological stress. Materials and Methods A total of 250 1-day-old (ross) chicks were divided into 5 groups; four of which were supplemented with 1.4%, 2.8%, 4.2%, and 5.6% N. sativa Linn., respectively. The four supplemented groups were challenged with Escherichia coli O157:H7 1.5×108 at a 14th day old. A total of 1050 samples (150 serum, 150 swab, and 750 organ samples) were collected and examined. Results A highly significant increase (p<0.01) in 5.6% N. sativa Linn. supplemented group in performance traits (body weight, weight gain, and performance index), biochemical parameters (proteinogram, liver enzymes, and creatinine), immunoglobulins concentration, and immune organs' weight. Meanwile, liver showed improvement of histoarchitecture without fibrosis. Heart showed a mild pericarditis with a mild degree of hydropic degeneration. Bursa, thymus, and spleen showed lymphoid hyperplasia. Conclusion A concentration of 5.6% N. sativa Linn. in broiler's feed can improve the immune response and subsequent resistance of broilers against diseases.
منابع مشابه
Black Cumin ( Nigella sativa) Supplementation in the Diet of Broilers Influences Liver Weight and Its Enzymes
An experiment was conducted to evaluate the effects of supplementing black cumin (Nigella sativa) seeds (BCS) in diet on performance, liver weight and enzymes of broilers.The experiment was conducted as a randomized complete block design. Two hundred forty day-old unsexed broiler chicks (Cobb 500) were divided into four groups and assigned to four feeding treatments, with four replicates of 15 ...
متن کاملEffect of hydroalcoholic extract of Nigella sativa L. on the immune system and blood protein components in mice
Background: Black seed (Nigella sativa L.) in traditional medicine is well known that the chemical composition of the immune system with many applications in traditional medicine to fight the infection. This study investigated the effect of the plant's role in the immune system and blood protein. Experimental: In this study male mice of Balb/c strain were divided into four groups test...
متن کاملEffect of hydroalcoholic extract of Nigella sativa L. on the immune system and blood protein components in mice
Background: Black seed (Nigella sativa L.) in traditional medicine is well known that the chemical composition of the immune system with many applications in traditional medicine to fight the infection. This study investigated the effect of the plant's role in the immune system and blood protein. Experimental: In this study male mice of Balb/c strain were divided into four groups test...
متن کاملComparison of effects of Echinacea purpurea juices and Nigella sativa seeds on performance, some blood parameters, carcass and meat quality of broilers
متن کامل
Nigella sativa Linn.– A comprehensive review
Nigella sativa Linn. (Family-Ranunculaceae) is a widely used medicinal plant throughout India and popular in various Indigenous System of Medicine like Ayurveda, Siddha, Unani and Tibb. The seeds are used as astringent, bitter, stimulant, diuretic, emmenagogue and anthelmintic. They are also useful in jaundice, intermittent fever, dyspepsia, paralysis, piles and skin diseases. The present revie...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 10 شماره
صفحات -
تاریخ انتشار 2017